NFkB p100/p52 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC, Ctrl

NFkB p100/p52 Antibody Blocking Peptide Summary

• Description: A Human NFkB p100/p52 antibody blocking peptide
  
  Source: Synthetic (Accession #: Q00653)
• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: NFKB2
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Antibody Competition
  • Control
• Application Notes: Control peptide should be used at 1.0 ug per 1.0 ul of antiserum in per assay.

Packaging, Storage & Formulations

• Storage: Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
• Buffer: No Buffer
• Preservative: 0.01% Sodium Azide
• Purity: >95%

Notes

Store vial at -20C prior to opening. Aliquot contents and freeze at -20C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.

Alternate Names for NFkB p100/p52 Antibody Blocking Peptide

• DNA-binding factor KBF2
• H2TF1
• Lymphocyte translocation chromosome 10 protein
• Lyt10
• LYT10LYT-10
• nuclear factor NF-kappa-B p100 subunit
• nuclear factor of kappa light chain gene enhancer in B-cells 2
• nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
• Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
• Oncogene Lyt-10
• p52

Background

The NFkappaB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A cDNA has been isolated that encodes an alternative DNA binding subunit of NFkappaB. It is synthesized as a protein that is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFkappaB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NFKB2
• Uniprot:
  • Q00653()
  • Q00653()
  • Q00653()
  • Q00653()