Neurophysin II/Arg-vasopressin Antibody (62865) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: IHC
• Clone: 62865
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

Neurophysin II/Arg-vasopressin Antibody (62865) [Alexa Fluor® 405] Summary

• Immunogen: Synthetic peptide containing human Neurophysin II
  Accession # P01186
• Specificity: Detects human Neurophysin II in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neurophysin II/Arg-vasopressin Antibody (62865) [Alexa Fluor® 405]

• arginine vasopressin
• ARVP
• AVP
• AVP-NPII
• AVRP
• neurohypophyseal
• Neurophysin II
• NP2
• vasopressin-neurophysin 2-copeptin
• VP

Background

Arginine vasopressin (AVP)/Neurophysin 2 is a hormone synthesized in neurons in the hypothalamus that specifically binds vasopressin.  Vasopressin has a direct antidiuretic action on the kidney and causes vasoconstriction of the peripheral vessels.  Vasopressin regulates the tonicity of body fluid by causing the kidneys to reabsorb solute-free water and returning it to the circulation from the tubules of the nephron.  AVP released in high concentrations may also raise blood pressure by inducing vasoconstriction.  The stimulus for secretion of vasopressin is increased osmolality of the plasma which is monitored by the hypothalamus.  Vasopressin is often used to manage anti-diuretic hormone deficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.