V2 Vasopressin R/AVPR2 Antibody

Images

 
Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS272] - Human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS272] - Analysis of anti-AVPR2 antibody with human kidney, renal tubules.
Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS272] - Human Lung, Adenocarcinoma. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mu, Rt, Ha, Mk, Rb, Po, Bt, Ca, Eq, PmSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

V2 Vasopressin R/AVPR2 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human AVPR2.
Localization
Cell Membrane
Specificity
Human AVPR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Porcine (90%), Bat (95%), Canine (90%), Primate (95%), Equine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AVPR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 26 ug/ml
Control
V2 Vasopressin R/AVPR2 Lysate (NBL1-07867)
Publications
Read Publication using
NLS272 in the following applications:

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Chimpanzee (100%), Gorilla (100%), Orangutan (100%), Gibbon (100%), Marmoset (100%), Elephant (100%), Baboon (95%), Armadillo (85%), Shrew (80%), Panda (80%), Bovine (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for V2 Vasopressin R/AVPR2 Antibody

  • ADHR
  • ADHRMGC138386
  • Antidiuretic hormone receptor
  • arginine vasopressin receptor 2
  • AVPR V2
  • AVPR2
  • DI1
  • DIR3
  • DIRNDI
  • NDI
  • Renal-type arginine vasopressin receptor
  • V2 Vasopressin R
  • V2 VasopressinR
  • V2R
  • V2RMGC126533
  • vasopressin V2 receptor

Background

The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for V2 Vasopressin R/AVPR2 Antibody (NLS272)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-Fr.


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IHC-Fr
(1)
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Mouse
(1)
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Product General Protocols

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Diseases for V2 Vasopressin R/AVPR2 Antibody (NLS272)

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Bioinformatics

Gene Symbol AVPR2
Entrez