Neprilysin/CD10 Antibody (LT10)

Product Discontinued

Neprilysin/CD10 Antibody (LT10) Summary

• Immunogen: Tissue cell preparation (Mouse Nalm6 cell line).
• Localization: Cell Membrane
• Specificity: NB110-7725 reacts with the surface antigen (MW 100 kDa) otherwise known as the common acute lymphoblastic leukemia antigen (CALLA).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MME
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunoassay 1:1000
• Application Notes: Immunoassay:NB110-7725 can be used to classify cases of leukemia

Reactivity Notes

Cross-reacts with Human.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Neprilysin/CD10 Antibody (LT10)

• Atriopeptidase
• CALLA
• CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)
• CD10 antigen
• CD10
• CD10)
• CD10membrane metallo-endopeptidase variant 1
• Common acute lymphocytic leukemia antigen
• DKFZp686O16152
• EC 3.4.24
• EC 3.4.24.11
• Enkephalinase
• EPN
• Leu-19
• membrane metallo-endopeptidase variant 2
• membrane metallo-endopeptidase
• MGC126681
• MGC126707
• MME
• NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA
• Neprilysin
• Neutral Endopeptidase 24.11
• Neutral endopeptidase
• NKH1
• SFE
• Skin fibroblast elastase

Background

Human CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt's lymphoma and chronic myelocytic leukemia. CD10 also marks normal early lymphoid progenitor cells, immature B-cells in adult bone marrow and germinal cells in normal tonsil and normal lymphoid tissue. It is also expressed in some non-lymphoid tissues such as fibroblasts, breast myoepithelium and brush border of kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MME
• Entrez:
  • 4311(Human)