NALP4 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 1 mg/ml

NALP4 Antibody Blocking Peptide Summary

• Specificity: This peptide is specific for NB100-56156 only.
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: NLRP4

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-56156. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Peptide dissolved in dH20. Contains no BSA.
• Preservative: No Preservative
• Concentration: 1 mg/ml

Alternate Names for NALP4 Antibody Blocking Peptide

• Cancer/testis antigen 58
• CLR19.5
• CT58PYRIN and NACHT-containing protein 2
• FLJ32126
• NACHT, leucine rich repeat and PYD containing 4
• NACHT, LRR and PYD domains-containing protein 4
• NALP4NACHT, LRR and PYD containing protein 4
• NLR family, pyrin domain containing 4
• nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 4
• PAN2Ribonuclease inhibitor 2
• PYPAF4PAAD and NACHT-containing protein 2
• RNH2PYRIN-containing APAF1-like protein 4

Background

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: NLRP4