NACA2 Antibody

Western Blot: NACA2 Antibody [H00342538-B01P] - Analysis of NACA2 expression in transfected 293T cell line by NACA2 polyclonal antibody. Lane 1: NACAL transfected lysate(23.65 KDa). Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: NACA2 Antibody [H00342538-B01P] - Analysis of purified antibody to NACAL on HepG2 cell. (antibody concentration 10 ug/ml)

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

NACA2 Antibody Summary

• Immunogen: NACAL (NP_954984.1, 1 a.a. - 215 a.a.) full-length human protein. MPGEATETVPATEQELPQSQAETGSGTASDSGESVPGIEEQDSTQTTTQKAWLVAAAEIDEEPVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIVFGEAKIQDLSQQAQLAAAEKFRVQGEAVGNIQENTQTPTVQEESEEEEVDETGVEVKDVKLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV
• Specificity: NACAL - nascent-polypeptide-associated complex alpha polypeptide-like,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: NACA2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Has also been used for immunofluorescence.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NACA2 Antibody

• alpha-NAC protein
• Alpha-NAC-like
• ANAC
• hom s 2.01 protein
• Hom s 2.01
• IgE autoantigen alpha-nascent polypeptide-associated complex
• MGC71999
• NACAL
• NAC-alpha-like
• nascent polypeptide-associated complex alpha subunit 2
• nascent polypeptide-associated complex subunit alpha-2
• Nascent polypeptide-associated complex subunit alpha-like
• nascent polypeptide-associated complex, alpha polypeptide, 2
• nascent-polypeptide-associated complex alpha polypeptide-like

Background

Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds tonascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognitionparticle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity ofribosomes for protein translocation sites in the ER membrane (M sites)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NACA2
• Entrez:
  • 342538(Human)
• Uniprot:
  • NP_954984.1(Human)