Myotrophin Antibody

Western Blot: Myotrophin Antibody [H00136319-B03P] - Analysis of MTPN expression in Jurkat.

Immunocytochemistry/Immunofluorescence: Myotrophin Antibody [H00136319-B03P] - Analysis of purified antibody to MTPN on HeLa cell. Antibody concentration 10 ug/ml

Western Blot: Myotrophin Antibody [H00136319-B03P] - Analysis of MTPN expression in transfected 293T cell line. Lane 1: MTPN transfected lysate (12.90 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

Myotrophin Antibody Summary

• Immunogen: MTPN (NP_665807.1, 1 a.a. - 118 a.a.) full-length human protein. MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ
• Specificity: Reacts with myotrophin.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: MTPN
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Myotrophin Antibody

• FLJ31098
• FLJ99857
• GCDP
• granule cell differentiation protein
• MYOTROPHIN
• Protein V-1
• V-1

Background

The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MTPN
• Entrez:
  • 136319(Human)
• Uniprot:
  • NP_665807.1(Human)