Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) [Alexa Fluor® 350]

Product Discontinued

Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) [Alexa Fluor® 350] Summary

• Immunogen: Myosin heavy chain from rabbit muscle
• Localization: Cytoplasm, myofibril. Note: thick filaments of the myofibrils.
• Specificity: NB100-65675 reacts strongly with human cardiac myosin and also recognizes rabbit myosin heavy and light chains.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MYH2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) [Alexa Fluor® 350]

• fast 2a myosin heavy chain
• MYH2
• MYH2A
• MYHas8
• MyHC-2a
• MyHC-IIa
• MYHSA2
• Myosin heavy chain 2
• myosin heavy chain 2a
• myosin heavy chain IIa
• myosin, heavy chain 2, skeletal muscle, adult
• myosin, heavy polypeptide 2, skeletal muscle, adult
• myosin-2
• skeletal muscle, adult 2
• type IIA myosin heavy chain

Background

Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYH2