Myosin heavy chain 2 Antibody (4G9) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: 4G9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

Myosin heavy chain 2 Antibody (4G9) [CoraFluor™ 1] Summary

• Immunogen: myosin, heavy chain 2, skeletal muscle, adult - (Uniprot# Q9UKX2)
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: MYH2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Myosin heavy chain 2 Antibody (4G9) [CoraFluor™ 1]

• fast 2a myosin heavy chain
• MYH2
• MYH2A
• MYHas8
• MyHC-2a
• MyHC-IIa
• MYHSA2
• Myosin heavy chain 2
• myosin heavy chain 2a
• myosin heavy chain IIa
• myosin, heavy chain 2, skeletal muscle, adult
• myosin, heavy polypeptide 2, skeletal muscle, adult
• myosin-2
• skeletal muscle, adult 2
• type IIA myosin heavy chain

Background

Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYH2