Recombinant Human Mxi1 GST (N-Term) Protein

Images

 
12.5% SDS-PAGE Stained with Coomassie Blue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, PA, AP

Order Details

Recombinant Human Mxi1 GST (N-Term) Protein Summary

Description
A recombinant protein with a N-terminal GST tag corresponding to the amino acid sequence 73-182 of Human Mxi1

Source: Wheat Germ (in vitro)

Amino Acid Sequence: LEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS

Preparation
Method
in vitro wheat germ expression system
Details of Functionality
This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
Source
Wheat germ
Protein/Peptide Type
Partial Recombinant Protein
Gene
MXI1
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Theoretical MW
37.84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human Mxi1 GST (N-Term) Protein

  • BHLHC11
  • Class C basic helix-loop-helix protein 11
  • MAD2
  • MAX dimerization protein 2
  • MAX interacting protein 1
  • MAX interactor 1bHLHc11MAD2
  • max-interacting protein 1
  • Max-related transcription factor
  • MGC43220
  • MXD2
  • MXI
  • Mxi1
  • MXI-WR

Background

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-89979
Species: Hu
Applications: IHC, IHC-P
NBP1-32775
Species: Hu, Mu, Rt
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
NB100-563
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
NB100-59828
Species: Hu, Mu
Applications: WB, IHC, IHC-P, IP
NB100-353
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IP, CyTOF-ready
NB600-335
Species: Hu, Mu, Ec, All-NA
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NB100-91662
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP2-66987
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
H00000699-D01P
Species: Hu, Mu
Applications: WB, ICC/IF, PLA
NBP1-88517
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, KD
NBP1-81765
Species: Hu
Applications: IHC, IHC-P
NBP2-24509
Species: Hu, Mu, Rt, Bv, Ca, Ma-Op, Pm
Applications: WB, IHC, IHC-P
MAB6028
Species: Hu
Applications: WB
NB100-793
Species: Hu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA, IF
NB100-1116
Species: Hu
Applications: ICC/IF, IHC, IHC-P, PEP-ELISA
NB100-56479
Species: Hu, Mu, Rt, Po, Bv, Ca, Pm
Applications: WB, ICC/IF, IHC, IHC-P
NB100-56507
Species: Hu, Mu, Rt
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P, IP, CyTOF-ready, KO
NB100-1103
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
NBP2-75659
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
NB200-103
Species: Hu, Mu, Rt, Ye, Xp(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready, Flow-IC

Publications for Mxi1 Partial Recombinant Protein (H00004601-Q01) (0)

There are no publications for Mxi1 Partial Recombinant Protein (H00004601-Q01).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Mxi1 Partial Recombinant Protein (H00004601-Q01) (0)

There are no reviews for Mxi1 Partial Recombinant Protein (H00004601-Q01). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Mxi1 Partial Recombinant Protein (H00004601-Q01) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Other Available Formats

Additional Mxi1 Products

Bioinformatics Tool for Mxi1 Partial Recombinant Protein (H00004601-Q01)

Discover related pathways, diseases and genes to Mxi1 Partial Recombinant Protein (H00004601-Q01). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Mxi1 Partial Recombinant Protein (H00004601-Q01)

Discover more about diseases related to Mxi1 Partial Recombinant Protein (H00004601-Q01).
 

Pathways for Mxi1 Partial Recombinant Protein (H00004601-Q01)

View related products by pathway.

PTMs for Mxi1 Partial Recombinant Protein (H00004601-Q01)

Learn more about PTMs related to Mxi1 Partial Recombinant Protein (H00004601-Q01).
 

Research Areas for Mxi1 Partial Recombinant Protein (H00004601-Q01)

Find related products by research area.

Blogs on Mxi1

There are no specific blogs for Mxi1, but you can read our latest blog posts.

Customers Who Bought This Also Bought

c-Myc Antibody
NB600-335

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Human Mxi1 GST (N-Term) Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol MXI1