Muscarinic Acetylcholine Receptor M5/CHRM5 Antibody (590123) [Unconjugated]

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HEK293 human embryonic kidney cell line transfected with either (A) human CHRM5 or (B) irrelevant protein and eGFP was stained with Mouse Anti-Human CHRM5 Monoclonal Antibody (Catalog # MAB10323) followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
590123
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Muscarinic Acetylcholine Receptor M5/CHRM5 Antibody (590123) [Unconjugated] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human  CHRM5
Met1-Pro532
Accession # P08912
Specificity
Detects human CHRM5 in diect ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Muscarinic Acetylcholine Receptor M5/CHRM5 Antibody (590123) [Unconjugated]

  • cholinergic receptor, muscarinic 5
  • CHRM5
  • HM5
  • M5
  • M5R
  • mAChR M5
  • MGC41838
  • muscarinic acetylcholine receptor M5

Background

Muscarinic receptors are widely distributed throughout the body and control distinct functions according to location and subtype (M1 - M5). They are predominantly expressed in the parasympathetic nervous system where they exert both inhibitory and excitatory effects. Stimulation of CHRM5 is known to increase cyclic AMP levels. The clinical implications of CHRM5 are unknown but it may be linked to schizophrenia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Muscarinic Acetylcholine Receptor M5/CHRM5 Antibody (MAB10323) (0)

There are no publications for Muscarinic Acetylcholine Receptor M5/CHRM5 Antibody (MAB10323).
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