Histamine H1R Antibody (480054)

Images

 
U937 human histiocytic lymphoma cell line treated with 50 ng/mL PMA for 24 hours was stained with Mouse Anti-Human Histamine H1 R Monoclonal Antibody (Catalog # MAB4726, filled histogram) or isotype control antibody ...read more
U937 human histiocytic lymphoma cell line was stained with Mouse Anti-Human Histamine H1 R Monoclonal Antibody (Catalog # MAB4726, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
480054
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Histamine H1R Antibody (480054) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Histamine H1 R
Met1-Ser487
Accession # AAH60802
Specificity
Detects human Histamine H1 R. Stains human Histamine H1 R transfectants but not irrelevant transfectants.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HRH1
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publications using
MAB4726 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Histamine H1R Antibody (480054)

  • H1R
  • H1-R
  • hisH1
  • Histamine H1 R
  • Histamine H1R
  • histamine receptor H1
  • HRH1
  • subclass H1

Background

Histamine H1 R (HRH1) is a 60 kDa, 487 aa G-protein coupled 7-transmembrane putative glycoprotein. It is implicated in the pathogenesis of asthma and is a major pharmaceutical target for antihistamines. It has been detected as a mixture of monomers and homodimers, with highest concentration in the placenta, followed by brain, lung (produced by airway smooth muscle, bronchial epithelium and macrophages) and other tissues. Extracellular domains of human HRH1 share 72% aa sequence identity with corresponding regions of mouse or rat HRH1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Histamine H1R Antibody (MAB4726)(2)

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Product General Protocols

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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol HRH1
Uniprot