Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody

Images

 
Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody [NLS220] - Analysis of anti-CHRM4 / M4 antibody with human lymph node, Hodgkins lymphoma.
Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody [NLS220] - Analysis of anti-CHRM4 / M4 antibody with human brain, neurons and glia.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Eq, Gp, Ha, Bt, Ca, PmSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CHRM4.
Specificity
Human CHRM4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Canine (95%), Bat (90%), Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHRM4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 - 20 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID: 23212463).
Publications
Read Publication using
NLS220 in the following applications:

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody

  • cholinergic receptor, muscarinic 4
  • CHRM4
  • HM4
  • M4
  • M4R
  • mAChR M4
  • muscarinic acetylcholine receptor M4

Background

Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody (NLS220)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.


Filter By Application
ICC/IF
(1)
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Filter By Species
Human
(1)
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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol CHRM4
Entrez
Uniprot