MUC19 Antibody (876013) [Alexa Fluor® 647]

• Applications: IHC
• Clone: 876013
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

MUC19 Antibody (876013) [Alexa Fluor® 647] Summary

• Immunogen: E. coli-derived recombinant human MUC-19
  Lys5606-Gly5767
  Accession # Q7Z5P9
• Specificity: Detects human MUC-19 in direct ELISAs.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

MUC-19 is a 6,254 amino acid member of the Mucin family of gel-forming glycoproteins.  MUC-19 is expressed in corneal epithelial cells in the eye, conjuctival goblet and epithelial cells and lacrimal gland cells as well as by mucous cells of the submandibular gland and submucosal gland of the trachea.  MUC-19 expression is reduced in patients with Sjogren syndrome (1,2). In a middle ear model of inflammatory response, MUC-19 is up-regulated in epithelial cells by exposure to cytokines including TNF-alpha, IL-1 beta, IL-5 and IL-8 (3).

 

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.