MUC19 Antibody (876013) [Alexa Fluor™ Plus 488]

• Clone: 876013
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

MUC19 Antibody (876013) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human MUC-19 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MUC19 Antibody (876013) [Alexa Fluor™ Plus 488]

• MUC19
• MUC-19

Background

MUC-19 is a 6,254 amino acid member of the Mucin family of gel-forming glycoproteins.  MUC-19 is expressed in corneal epithelial cells in the eye, conjuctival goblet and epithelial cells and lacrimal gland cells as well as by mucous cells of the submandibular gland and submucosal gland of the trachea.  MUC-19 expression is reduced in patients with Sjogren syndrome (1,2). In a middle ear model of inflammatory response, MUC-19 is up-regulated in epithelial cells by exposure to cytokines including TNF-alpha, IL-1 beta, IL-5 and IL-8 (3).

 

1. Yu, D. et al. (2008) Exp Eye Res. 86 :403.
2. Chen, Y. et al. (2004) Am J Respir Cell Mol Biol 30:155.
3. Kerschner, J. et al. (2009) Glycoconj J. 26:1275.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.