Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Mouse IL-17B DuoSet ELISA, 15 Plate
Cytokine Zcyto7
cytokine-like protein ZCYTO7
IL17B
IL-17B
IL-17Binterleukin-17 beta
IL20
IL-20interleukin-17B
interleukin 17B
interleukin 20
Interleukin-20
MGC138900
MGC138901
neuronal interleukin-17 related factor
Neuronal interleukin-17-related factor
NIRF
ZCYTO7interleukin-20
Background
The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.