Mouse Cystatin C DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse Cystatin C DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Cst3

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Cystatin C DuoSet ELISA, 15 Plate

• ARMD11
• bA218C14.4 (cystatin C)
• CST3
• cystatin 3
• cystatin C (amyloid angiopathy and cerebral hemorrhage)
• Cystatin C
• Cystatin-3
• cystatin-C
• Gamma-trace
• MGC117328
• Neuroendocrine basic polypeptide
• Post-gamma-globulin

Background

Cystatin C is a secreted cysteine protease inhibitor that inhibits Cathepsins B, H, K, L, and S. Cystatin C serum concentration correlates closely to the glomerular filtration rate (GFR); elevated levels are associated with coronary artery and cardiovascular disease risk. Dysregulation of Cystatin C can modulate tumor growth and metastasis. In humans, the L68Q variant forms dimers and oligomers more easily than wild type protein and is the cause for hereditary Cystatin C amyloid angiopathy.

Publications for Cystatin C (DY1238)(4)

Publications using DY1238

• Dørflinger, GH;Holt, CB;Thiel, S;Bech, JN;Østergaard, JA;Bjerre, M; Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes International journal of molecular sciences 2024-06-29 [PMID: 39000309] (Mouse)
• Andreev, D;Kachler, K;Liu, M;Chen, Z;Krishnacoumar, B;Ringer, M;Frey, S;Krönke, G;Voehringer, D;Schett, G;Bozec, A; Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase Nature communications 2024-02-05 [PMID: 38316791] (Transgenic Mouse)
• Ferreira, P;Vaja, R;Lopes-Pires, M;Crescente, M;Yu, H;Nüsing, R;Liu, B;Zhou, Y;Yaqoob, M;Zhang, A;Rickman, M;Longhurst, H;White, WE;Knowles, RB;Chan, MV;Warner, TD;Want, E;Kirkby, NS;Mitchell, JA; Renal Function Underpins the Cyclooxygenase-2: Asymmetric Dimethylarginine Axis in Mouse and Man Kidney international reports 2023-06-01 [PMID: 37284684] (Mouse)
• Xu Y, Schnorrer P, Proietto A, Kowalski G, Febbraio MA, Acha-Orbea H, Dickins RA, Villadangos JA IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression. J. Immunol., 2011-02-07;186(6):3666-73. 2011-02-07 [PMID: 21300820] (Mouse)

Bioinformatics

• Gene Symbol: Cst3