Mouse Complement Factor D/Adipsin DuoSet ELISA, 5 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse Complement Factor D/Adipsin DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: cfd

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Complement Factor D/Adipsin DuoSet ELISA, 5 Plate

• Adipsin
• ADN
• ADNcomplement factor D
• AMBP-1
• C3 convertase activator
• CFD
• complement factor D (adipsin)
• complement factor D preproprotein
• Complement Factor D
• D component of complement (adipsin)
• DF
• EC 3.4.21
• EC 3.4.21.46
• PFD
• Properdin factor DADIPSIN

Background

Complement Factor D, also known as adipsin, is a serine protease that catalyzes the initial proteolytic step in the alternative pathway of complement. It is an exceptionally specific protease and the only known protein substrate is factor B in complex with C3.3 Factor D protease activity is regulated by reversible conformational changes, which differs from the majority of serine proteases whose regulation involves either activation by processing of the zymogens or inactivation by binding of the inhibitors.

Publications for Complement Factor D/Adipsin (DY5430-05)(3)

Publications using DY5430-05

• T Pemmari, M Hämäläinen, R Ryyti, R Peltola, E Moilanen Dried Bilberry (Vaccinium myrtillus L.) Alleviates the Inflammation and Adverse Metabolic Effects Caused by a High-Fat Diet in a Mouse Model of Obesity International Journal of Molecular Sciences, 2022-09-20;23(19):. 2022-09-20 [PMID: 36232316] (Mouse)
• W Zou, N Rohatgi, JR Brestoff, Y Zhang, EL Scheller, CS Craft, MD Brodt, N Migotsky, MJ Silva, CA Harris, SL Teitelbaum Congenital lipodystrophy induces severe osteosclerosis PLoS Genet., 2019-06-24;15(6):e1008244. 2019-06-24 [PMID: 31233501] (Mouse)
• M Rödiger, MW Werno, I Wilhelmi, C Baumeier, D Hesse, N Wettschure, S Offermanns, K Song, M Krau beta , A Schürmann Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes Mol Metab, 2017-11-22;0(0):. 2017-11-22 [PMID: 29203237] (Mouse)

Bioinformatics

• Gene Symbol: cfd