Mouse CCL22/MDC DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL22/MDC DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl22

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL22/MDC DuoSet ELISA, 15 Plate

• A-152E5.1
• ABCD-1
• CC chemokine STCP-1
• C-C motif chemokine 22
• CCL22
• chemokine (C-C motif) ligand 22
• DC/B-CK
• Macrophage-derived chemokine
• MDC
• MDCStimulated T-cell chemotactic protein 1
• MGC34554
• SCYA22MDC(1-69)
• small inducible cytokine A22
• small inducible cytokine subfamily A (Cys-Cys), member 22
• Small-inducible cytokine A22
• STCP-1
• stimulated T cell chemotactic protein 1

Background

Macrophage-derived chemokine (MDC), also named stimulated T cell chemotactic protein (STCP-1) and ABCD-1, and now designated as CCL22, is a CC chemokine initially isolated from clones of monocyte-derived macrophages. At the amino acid sequence level, MDC shows less than 35% identity to other CC chemokine family members. Human MDC is expressed in dendritic cells, macrophages and activated monocytes. In addition, MDC expression is detected in thymus, lymph node and appendix tissues. At the amino acid sequence level, mouse and human MDC share 64% identity and 83% similarity.

Publications for CCL22/MDC (DY439)(12)

Publications using DY439

• Cook, PC;Brown, SL;Houlder, EL;Furlong-Silva, J;Conn, DP;Colombo, SAP;Baker, S;Svedberg, FR;Howell, G;Bertuzzi, M;Boon, L;Konkel, JE;Thornton, CR;Allen, JE;MacDonald, AS; Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice Nature communications 2025-01-22 [PMID: 39843887] (Mouse)
• Pereira, M;Ramalho, T;Andrade, WA;Durso, DF;Souza, MC;Fitzgerald, KA;Golenbock, DT;Silverman, N;Gazzinelli, RT; The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection Cell reports 2024-02-15 [PMID: 38367238] (Mouse)
• W Zhang, X Jiang, Y Zou, L Yuan, X Wang Pexidartinib synergize PD-1 antibody through inhibiting treg infiltration by reducing TAM-derived CCL22 in lung adenocarcinoma Frontiers in Pharmacology, 2023-03-08;14(0):1092767. 2023-03-08 [PMID: 36969873] (Mouse)
• AE Pottash, D Levy, A Jeyaram, L Kuo, SM Kronstadt, W Chao, SM Jay Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy Non-coding RNA, 2022-10-21;8(5):. 2022-10-21 [PMID: 36287123] (Mouse)
• ZS Wong, SL Sokol-Borr, P Olias, JP Dubey, JP Boyle Head-to-head comparisons of Toxoplasma gondii and its near relative Hammondia hammondi reveal dramatic differences in the host response and effectors with species-specific functions PLoS Pathog., 2020-06-23;16(6):e1008528. 2020-06-23 [PMID: 32574210] (Mouse)
• Niven J, Hoare J, McGowan D, Devarajan G, Itohara S, Gannage M, Teismann P, Crane I S100B Up-Regulates Macrophage Production of IL1beta and CCL22 and Influences Severity of Retinal Inflammation. PLoS ONE, 2015-07-23;10(7):e0132688. 2015-07-23 [PMID: 26204512] (Mouse)
• Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat Immunol, 2015-06-15;16(8):850-8. 2015-06-15 [PMID: 26075911] (Mouse)
• Jha A, Huang S, Sergushichev A, Lampropoulou V, Ivanova Y, Loginicheva E, Chmielewski K, Stewart K, Ashall J, Everts B, Pearce E, Driggers E, Artyomov M Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization. Immunity, 2015-03-17;42(3):419-30. 2015-03-17 [PMID: 25786174] (Mouse)
• Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration. Eur. J. Immunol., 2012-05-01;42(5):1226-36. 2012-05-01 [PMID: 22539295] (Mouse)
• van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid. J. Neurochem., 2010-06-16;114(5):1511-26. 2010-06-16 [PMID: 20557428] (Mouse)
• Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes. J. Immunol., 2007-12-15;179(12):8381-91. 2007-12-15 [PMID: 18056384] (Human)
• Carpenter KJ, Hogaboam CM Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis. Infect. Immun., 2005-11-01;73(11):7198-207. 2005-11-01 [PMID: 16239514] (Mouse)

FAQs for CCL22/MDC (DY439). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Ccl22