MNK2 Antibody - BSA Free

Western Blot: MNK2 Antibody [NBP1-92129] - Analysis in human cell line SK-MEL-30.

Immunohistochemistry-Paraffin: MNK2 Antibody [NBP1-92129] - Staining of human gall bladder shows moderate cytoplasmic and nuclear positivity in glandular cells.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

MNK2 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: ELQGFHRSFKGQNPFELAFSLDQPDHGDSDFGLQCSARPDMPASQPIDIPDAKKRGKKKKRGRATDSFSGRFEDVYQLQEDVLGEGAHARVQTCINLITSQE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MKNK2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:10-1:20
  • Western Blot 0.04 - 0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  MNK2 Protein (NBP1-92129PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (88%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for MNK2 Antibody - BSA Free

• EC 2.7.11
• EC 2.7.11.1
• G protein-coupled receptor kinase 7
• GPRK7Putative map kinase interacting kinase
• MAP kinase interacting serine/threonine kinase 2
• MAP kinase signal-integrating kinase 2
• MKNK2
• MNK2
• MNK2MAP kinase-interacting serine/threonine-protein kinase 2

Background

MNK2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription byphosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MKNK2