MMP-16/MT3-MMP Antibody Summary
Recombinant protein encompassing a sequence within the center region of human MMP16. The exact sequence is proprietary.
Isoform Long: Cell membrane, Single-pass type I membrane protein, Extracellular side (Potential), Isoform Short: Secreted, extracellular space, extracellular matrix, Cell surface
Chicken (98%), Bovine (98%), Xenopus (92%). Backed by our 100% Guarantee.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1:500-1:3000
- Immunohistochemistry 1:100-1:1000
- Immunohistochemistry-Paraffin 1:100-1:1000
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Xenopus laevis (92%), Japanese Medaka (83%).
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Immunogen affinity purified
Alternate Names for MMP-16/MT3-MMP Antibody
- chromosome 8 open reading frame 57
- EC 3.4.24
- EC 3.4.24.-
- EC 188.8.131.52
- matrix metallopeptidase 16 (membrane-inserted)
- matrix metalloproteinase 16 (membrane-inserted)
- matrix metalloproteinase-16
- Membrane-type matrix metalloproteinase 3
- Membrane-type-3 matrix metalloproteinase
- MT-MMP 3
- Putative transmembrane protein C8orf57
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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