Reactivity | Hu, MuSpecies Glossary |
Applications | WB, Flow, IHC, IP |
Clone | M5/114.15.2 |
Clonality | Monoclonal |
Host | Rat |
Conjugate | FITC |
Immunogen | The immunogen for this antibody was MHC Class II. |
Specificity | The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes. |
Isotype | IgG2b Kappa |
Clonality | Monoclonal |
Host | Rat |
Gene | H2-Ea |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | PBS |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for MHC class II (I-A/I-E) Antibody (NBP1-43312F)Find related products by research area.
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Gene Symbol | H2-Ea |