MgcRacGAP/RACGAP1 Antibody

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Western Blot: MgcRacGAP/RACGAP1 Antibody [NBP1-47267] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

MgcRacGAP/RACGAP1 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 150 and 200 of human Rac GTPase-Activating Protein 1 using the numbering given in entry NP_001119575.1 (GeneID 29127).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RACGAP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 5-15 ug/mg lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MgcRacGAP/RACGAP1 Antibody

  • GTPase activating protein
  • HsCYK-4
  • ID-GAP
  • KIAA1478
  • Male germ cell RacGap
  • MgcRacGAP
  • MgcRacGAPrac GTPase-activating protein 1
  • Rac GTPase activating protein 1
  • RACGAP1

Background

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RACGAP1
Entrez