Methionine Aminopeptidase 2/METAP2 Antibody [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor Plus 680

Methionine Aminopeptidase 2/METAP2 Antibody [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human Methionine Aminopeptidase 2/METAP2 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Methionine Aminopeptidase 2/METAP2 Antibody [Alexa Fluor™ Plus 680]

• Amp2
• eIF-2-associated p67 homolog
• Initiation factor 2-associated 67 kDa glycoprotein
• MAP 2
• MAP2
• MetAP 2
• METAP2
• Methionine Aminopeptidase 2
• methionyl aminopeptidase 2
• MNPEP
• p67
• p67EC 3.4.11.18
• p67eIF2
• Peptidase M 2

Background

The human METAP2 gene encodes Methionine Aminopeptidase 2, a member of the M24 family of metalloproteases. METAPs catalyze the removal of the initiator methionine residue from nascent peptides (1) and are essential for cell growth (2). METAP2 plays an important role in the development of different types of cancer (3) and has been a novel target for developing anti-cancer drugs.

1. Lowther, W.T. and B.W. Matthews (2000) Biochim. Biophys. Acta 1477:157.
2. Li, X. and Y.H. Chang (1995) Proc. Natl. Acad. Sci. USA 92:12357.
3. Selvakumar, P. et al. (2006) Biochim. Biophys. Acta 1765:148.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.