Methionine Aminopeptidase 2/METAP2 Products

Antibodies
Methionine Aminopeptidase 2/M ...
Methionine Aminopeptidase 2/METAP2...
AF3795
Species: Hu
Applications: WB, IP
Host: Sheep Polyclonal
Proteins
Methionine Aminopeptidase 2/M ...
Methionine Aminopeptidase 2/METAP2...
H00010988-P01
Species: Hu
Applications: WB, ELISA, PA

Description

METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]

Bioinformatics

Product By Gene ID 10988
Alternate Names
  • MNPEP
  • methionyl aminopeptidase 2
  • p67
  • Peptidase M 2
  • P67EIF2
  • MetAP 2
  • methionine aminopeptidase 2
  • Initiation factor 2-associated 67 kDa glycoprotein
  • eIF-2-associated p67 homolog
  • MAP2
  • p67EC 3.4.11.18
  • MAP 2
  • methionyl aminopeptidase 2

PTMs for Methionine Aminopeptidase 2/METAP2

Learn more about PTMs related to Methionine Aminopeptidase 2/METAP2.

Phosphorylation
Cleavage
Glycosylation
Myristoylation
Methylation
Deglycosylation

Bioinformatics Tool for Methionine Aminopeptidase 2/METAP2

Discover related pathways, diseases and genes to Methionine Aminopeptidase 2/METAP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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