MafG Antibody (370412) [DyLight 350]

• Reactivity: Hu
• Applications: WB
• Clone: 370412
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 350

MafG Antibody (370412) [DyLight 350] Summary

• Immunogen: E. coli-derived recombinant human MafG
  Met1-Ser162
  Accession # O15525
• Specificity: Detects human MafG in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) MafF or rhMafK is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: MAFG
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MafG Antibody (370412) [DyLight 350]

• basic leucine zipper transcription factor MafG
• hMAF
• MafG
• MGC13090
• MGC20149
• transcription factor MafG
• v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G
• v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
• V-maf musculoaponeurotic fibrosarcoma oncogene homolog G

Background

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAFG