MafG Products

Description

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+)

Bioinformatics

Entrez	4097 Human
Uniprot	NM_032711 Human NP_002350 Human NP_002350.1 Human NP_116100 Human O15525 Human
Product By Gene ID	4097
Alternate Names	basic leucine zipper transcription factor MafG hMAF MGC13090 MGC20149 transcription factor MafG v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) V-maf musculoaponeurotic fibrosarcoma oncogene homolog G