MAD2L1-binding protein Antibody

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-MAD2L1BP )

Product Discontinued

MAD2L1-binding protein Antibody Summary

• Immunogen: The immunogen for this antibody was a sequence from 1a.a. to 126a.a. from MAD2L1 binding protein(a 274a.a. long protein)
• Localization: Nuclear
• Specificity: MAD2L1-binding protein
• Clonality: Polyclonal
• Host: Chicken
• Gene: MAD2L1BP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000
• Application Notes: Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
• Control:

  MAD2L1-binding protein Overexpression Lysate

Reactivity Notes

This antibody is reactive against Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for MAD2L1-binding protein Antibody

• Caught by MAD2 protein
• CMT2MGC11282
• dJ261G23.1
• KIAA0110RP1-261G23.6
• MAD2L1 binding protein
• MAD2L1-binding protein

Background

May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAD2L1BP
• Entrez:
  • 9587(Human)
• Uniprot:
  • Q15013(Human)