Lymphotoxin Antibody (135125) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: B/N
• Clone: 135125
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

Lymphotoxin Antibody (135125) [Alexa Fluor® 532] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Lymphotoxin α/β
• Specificity: Recognizes human Lymphotoxin alpha chains in alpha ₂ beta ₁ or alpha ₁ beta ₂ trimers and also human TNF-beta . In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhEDA-A2, rhFas Ligand, rhLIGH
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Neutralization

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Lymphotoxin Antibody (135125) [Alexa Fluor® 532]

• LT
• Lymphotoxin alpha
• Lymphotoxin
• tnfb
• TNFSF1
• TNLG1E

Background

Lymphotoxin alpha , also known as tumor necrosis factor (TNF) beta , and Lymphotoxin beta are members of the TNF superfamily and have been designated TNFSF1 and TNFSF3, respectively. Secreted Lymphotoxin alpha forms a homotrimer (TNF­beta) and heterotrimeric complexes with the type II membrane protein, Lymphotoxin beta (either alpha 2 beta 1or alpha 1 beta 2 timers). These trimers serve as ligands for Lymphotoxin beta receptor, TNF RI and TNF RII and play a role in the development and maturation of the immune system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.