LXR beta/NR1H2 Antibody (K8917)

• Reactivity: Hu
• Applications: WB, IP, ELISA
• Clone: K8917
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

LXR beta/NR1H2 Antibody (K8917) Summary

• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: NR1H2

Applications/Dilutions

• Dilutions:
  • Direct ELISA
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Buffer: A liquid formulation in physiologic saline with 0.1% NaN₃.
• Preservative: 0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LXR beta/NR1H2 Antibody (K8917)

• Liver X receptor beta
• LXR beta
• LXR-b
• NER-I
• NERliver X receptor-beta
• NR1H2
• nuclear orphan receptor LXR-beta
• Nuclear receptor NER
• Nuclear receptor subfamily 1 group H member 2
• nuclear receptor subfamily 1, group H, member 2
• oxysterols receptor LXR-beta
• RIP15
• steroid hormone-nuclear receptor NER
• Ubiquitously-expressed nuclear receptorLXRB
• UNR
• UNRLX receptor beta

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LXR beta/NR1H2 Antibody (PP-K8917-00)(5)

Publications using PP-K8917-00

• Premaratne, A;Basu, S;Bagchi, A;Zhou, T;Feng, Q;Lin, CY; Liver X Receptor Ligand GAC0001E5 Downregulates Antioxidant Capacity and ERBB2/HER2 Expression in HER2-Positive Breast Cancer Cells Cancers 2024-04-25 [PMID: 38730603] (Western Blot, Human)
• A Premaratne, C Ho, S Basu, AF Khan, T Bawa-Khalf, CY Lin Liver X Receptor Inverse Agonist GAC0001E5 Impedes Glutaminolysis and Disrupts Redox Homeostasis in Breast Cancer Cells Biomolecules, 2023-02-10;13(2):. 2023-02-10 [PMID: 36830714] (Western Blot, Human)
• Fan Q, Norgaard RC, Grytten I et al. LXR alpha Regulates ChREBP alpha Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction Cells 5/13/2020 [PMID: 32414201]
• Dong B, Kan C, Singh A, Liu J High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway. J Lipid Res, 2013-02-20;54(5):1241-54. 2013-02-20 [PMID: 23427282] (Western Blot, Hamster)
• Minhao Wu, Bin Dong, Aiqin Cao, Hai Li, Jingwen Liu Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters Atherosclerosis 2012-10-01 [PMID: 22954675]

Bioinformatics

• Gene Symbol: NR1H2