LRRK2 Antibody Pack

Immunohistochemistry-Frozen: LRRK2 Antibody Pack [NB100-938] - Staining of muscle sections as described in PMID 24312256. Image from verified customer review. LRRK2 Antibody [NB300-268]

Western Blot: LRRK2 Antibody Pack [NB100-938] - LRRK2 N-terminal sequences show increased aggregation. Western blots of cell lysates of SH-SY5Y cells transfected with indicated LRRK2 construct showed equal expression of the LRRK2 protein with anti-HA (top panel) or anti-C-terminal- (bottom panel) LRRK2 antibody. Equal lysate loading is indicated by Beta-actin loading control. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0045149) licensed under a CC-BY licence. LRRK2 Antibody [NB300-268]

Immunohistochemistry: LRRK2 Antibody Pack [NB100-938] - Staining of neurons and glia using NB110-55289 at 2.5ug/ml. Mouse brain, 40x.

Knockout Validated: LRRK2 Antibody Pack [NB100-938] - Mn increases LRRK2 kinase activity and expression in RAW 264.7 and HMC3 cells. Two-hundred (200) ug of protein were collected from cell lysates, followed by western blot analysis to determine the presence of LRRK2 in LRRK2 WT, KO RAW 264.7 and HMC3 cells. Beta-actin was used as a loading control. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0210248) licensed under a CC-BY licence. LRRK2 Antibody [NB300-268]

Western Blot: LRRK2 Antibody Pack [NB100-938] - Detection of murine LRRK2 in mouse brain lysate using NB110-55289.

• Reactivity: Hu, Mu, Bv
• Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KO
• Host: Rabbit

LRRK2 Antibody Pack Summary

• Immunogen: See individual datasheets.
• Host: Rabbit
• Gene: LRRK2

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Knockout Validated
  • Western Blot
• Application Notes: See individual datasheets for validated applications.

Reactivity Notes

See individual datasheets.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.

Notes

This pack contains 1 vial each of: NB110-55289 (0.1 mL) and NB300-268 (0.1 mL).

Alternate Names for LRRK2 Antibody Pack

• augmented in rheumatoid arthritis 17
• AURA17
• Dardarin
• DKFZp434H2111
• EC 2.7.11.1
• FLJ45829
• leucine-rich repeat kinase 2
• leucine-rich repeat serine/threonine-protein kinase 2
• LRRK2
• PARK8
• PARK8DARDARIN
• Parkinson disease (autosomal dominant) 8
• RIPK7
• ROCO2

Background

We know how important it is to your research to have access to antibodies specific for your model. As it is often impossible to know which antibody will work best for a specific sample and application, we now offer SuperNovus Packs. These packs include different antibodies to the same protein to give you the ability to decide for yourself. The SuperNovus Packs are all offered at a discount price compared to purchasing each antibody individually. LRRK2 is a 286 kDa protein belonging to the ROCO family. It is a multifunction protein involved in Parkinson's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Packs are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LRRK2