Reactivity | Hu, Mu, Bv, Ce, I, Pl, Hu(-)Species Glossary |
Applications | WB, Flow, ICC/IF, IHC, IP, KO |
Description | This pack contains 1 vial each of: NB110-55289 (0.1 mL) and NB300-268 (0.1 mL). |
Immunogen | See individual datasheets. |
Gene | LRRK2 |
Dilutions |
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Application Notes | See individual datasheets of components for their validated applications |
Storage | Store at 4C. Do not freeze. |
Research Areas for LRRK2 Antibody Pack (NB100-938)Find related products by research area.
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The role of Parkin and autophagy in retinal pigment epithelial cell (RPE) degradation The root of Parkinson’s disease (PD) points to a poorly regulated electron transport chain leading to mitochondrial damage, where many proteins need to work cohesively to ensure proper function. The two key players of this pathway are PINK1, ... Read full blog post. |
The identification of dopaminergic neurons using Tyrosine Hydroxylase in Parkinson's research and LRRK2 Tyrosine hydroxylase (TH) is a crucial enzyme involved in the biosynthesis of dopamine, norepinephrine and epinephrine in the brain. Specifically, TH catalyzes the conversion of l-tyrosine to l-dihydroxyphenylalanine (l-dopa). The importance of t... Read full blog post. |
Parkinson's Disease Infographic Parkinson's disease affects the nervous system which controls movement. Damage to the levels of dopamine in the brain impairs the ability to relay messages to parts of the body which control movement. While the exact cause of the disease is unknown, r... Read full blog post. |
Novus Antibodies Highlighted in Parkinson's Disease Research Identified almost two centuries ago, Parkinson's disease is a neurodegenerative disorder that afflicts an estimated 4-6 million worldwide (www.parkinsons.org). The prevalence of Parkinson's disease is expected to grow considerably as the average age o... Read full blog post. |
Gene Symbol | LRRK2 |