LRRK2 Products

Antibodies
Antibody Packs
LRRK2 Antibody Pack
LRRK2 Antibody Pack
Species: Hu, Mu, Bv
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit
Proteins
LRRK2 Blocking Peptide
LRRK2 Blocking Peptide
NB300-268PEP
Species: Hu
LRRK2 Blocking Peptide
LRRK2 Blocking Peptide
NB110-55289PEP
Species: Hu

Description

LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

LRRK2 antibodies are useful tools for neurodegeneration research and certian kinase signaling pathway studies.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Mouse
Product By Gene ID 120892
Alternate Names
  • Parkinson disease (autosomal dominant) 8
  • EC 2.7.11.1
  • FLJ45829
  • Dardarin
  • DKFZp434H2111
  • leucine-rich repeat serine/threonine-protein kinase 2
  • ROCO2
  • augmented in rheumatoid arthritis 17
  • RIPK7
  • PARK8DARDARIN
  • AURA17
  • leucine-rich repeat kinase 2

Research Areas for LRRK2

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Neurodegeneration
Neuronal Cell Markers
Neuroscience
Phospho-Specific
Protein Kinase

Bioinformatics Tool for LRRK2

Discover related pathways, diseases and genes to LRRK2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related LRRK2 Blog Posts

Check out the latest blog posts on LRRK2.
The role of Parkin and autophagy in retinal pigment epithelial cell (RPE) degradation
The root of Parkinson’s disease (PD) points to a poorly regulated electron transport chain leading to mitochondrial damage, where many proteins need to work cohesively to ensure proper function.¬† The two key players of this pathway are PINK1,...    Read more.
The identification of dopaminergic neurons using Tyrosine Hydroxylase in Parkinson's research and LRRK2
Tyrosine hydroxylase (TH) is a crucial enzyme involved in the biosynthesis of dopamine, norepinephrine and epinephrine in the brain. ¬†Specifically, TH catalyzes the conversion of l-tyrosine to l-dihydroxyphenylalanine (l-dopa).¬† The importance of t...    Read more.
Parkinson's Disease Infographic
Parkinson's disease affects the nervous system which controls movement. Damage to the levels of dopamine in the brain impairs the ability to relay messages to parts of the body which control movement. While the exact cause of the disease is unknown, r...    Read more.
Novus Antibodies Highlighted in Parkinson's Disease Research
Identified almost two centuries ago, Parkinson's disease is a neurodegenerative disorder that afflicts an estimated 4-6 million worldwide (www.parkinsons.org). The prevalence of Parkinson's disease is expected to grow considerably as the average age o...    Read more.
Read more LRRK2 related blogs.