LOX Antibody [DyLight 488]


There are currently no images for LOX Antibody (NB100-2527G).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity Hu, Mu, Rt, Bovine, Chicken, PorcineSpecies Glossary
Applications WB, IHC, IHC-P
Please see the vial label for concentration. If unlisted please contact technical services.

LOX Antibody [DyLight 488] Summary

A synthetic peptide made to an internal region of the human LOX protein (within residues 200-300). [Swiss-Prot P28300].
Secreted, extracellular space.
Predicted Species
Porcine (100%), Chicken (92%), Bovine (92%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 488
DyLight 488 (A=493, E=518)
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


  • Western Blot 0.5-4ug/ml
  • Immunohistochemistry 1:100-1:250
  • Immunohistochemistry-Paraffin 1:100-1:250
Application Notes
This LOX antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry-paraffin embedded sections, and Western blot. In Western blot bands are observed ~58 kDa representing glycosylated Lox and ~32 kDa representing the mature, secreted form of Lox. In ICC/IF nuclear staining was observed in HeLa cells, which is expected for the mature form of LOX according to published literature (PMID 17287363 and 10996848).

Reactivity Notes

Human and mouse. Rat reactivity reported in scientific literature (PMID: 27169768). Predicted to react with rat pig based on 100% sequence homology. Immunogen sequence has 92% homology to cow and chicken and 85% homology to Xenopus.


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for LOX Antibody [DyLight 488]

  • lysyl oxidaseEC
  • MGC105112
  • protein-lysine 6-oxidase


Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: IHC, IHC-P
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF
Species: Hu, Rt, Ca, Mk, Pm
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ELISA
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB
Species: Hu, Rt, Ca, Mk
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Species: Hu, Mu, Rt, Bovine, Chicken, Porcine
Applications: WB, IHC, IHC-P

Publications for LOX Antibody (NB100-2527G) (0)

There are no publications for LOX Antibody (NB100-2527G).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for LOX Antibody (NB100-2527G) (0)

There are no reviews for LOX Antibody (NB100-2527G). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for LOX Antibody (NB100-2527G) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Other Available Formats

Biotin Labeled NB100-2527B
DyLight 550 Labeled NB100-2527R
DyLight 650 Labeled NB100-2527C
HRP Labeled NB100-2527H

Additional LOX Antibody [DyLight 488] Products

Related Products by Gene

Bioinformatics Tool for LOX Antibody (NB100-2527G)

Discover related pathways, diseases and genes to LOX Antibody (NB100-2527G). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for LOX Antibody (NB100-2527G)

Discover more about diseases related to LOX Antibody (NB100-2527G).

Pathways for LOX Antibody (NB100-2527G)

View related products by pathway.

PTMs for LOX Antibody (NB100-2527G)

Learn more about PTMs related to LOX Antibody (NB100-2527G).

Research Areas for LOX Antibody (NB100-2527G)

Find related products by research area.

Blogs on LOX.

LOX: A prime enzyme
LOX is a copper-dependent amine oxidase enzyme that executes post-translational oxidative deamination on peptidyl lysine residues in precursors of fibrous collagen and elastin. LOX is secreted into the extracellular environment in an inactive form, wh...  Read full blog post.

Understanding DNA Recombination with Cre-Lox
Cyclization recombination enzyme (Cre) is a member of the extensive family of recombinases and recognizes a 34 bp sequence motif from PI bacteriophage referred to as LoxP. The Cre enzyme works to cleanly excise an intervening DNA fragment that is flan...  Read full blog post.

Cre/Lox: The Genomic Utility Knife
Cre (Cyclization recombination enzyme) is a member of the large family of recombinases. Cre recognizes Lox site loxP, a 34 bp sequence motif from the PI bateriophage. If a DNA segment is flanked by two loxP sites in the same orientation, Cre neatly ex...  Read full blog post.

LOX propeptide: A novel peptide cancer therapeutic
Lysyl oxidase, also known as LOX, is a copper-dependent enzyme that cross-links collagen and elastin through the oxidative deamination of peptidyl lysine (collagen and elastin) and hydroxylysine (collagen only) residues, thereby playing a critical rol...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol LOX

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NB100-2527G below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought

LOX Antibody [HRP]
LOX Peptide
LOX Peptide
COX-2 Antibody
COX-2 Antibody
COX-2 Antibody