Hu, Mu, Rt, Po, Po, Bv, ChApplications:
WB, Simple Western, ICC/IF, IHC, IHC-P, KDHost:
Hu, Mu, Rt, Po, ShApplications:
WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KOHost:
Hu, Mu, Rt, Po, Bv, Ch, Xp, ZeApplications:
WB, Simple Western, ICC/IF, IHC, IHC-PHost:
Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. LOX plays a vital role in the formation and repair of the extracellular matrix. In addition, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, Lysyl oxidase is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
|Product By Gene ID
- protein-lysine 6-oxidase
- lysyl oxidaseEC 220.127.116.11
Bioinformatics Tool for LOX
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Related LOX Blog Posts
Check out the latest blog posts on LOX.
Read more LOX related blogs.
|LOX: A prime enzyme
LOX is a copper-dependent amine oxidase enzyme that executes post-translational oxidative deamination on peptidyl lysine residues in precursors of fibrous collagen and elastin. LOX is secreted into the extracellular environment in an inactive form, wh... Read more.
|Understanding DNA Recombination with Cre-Lox
Cyclization recombination enzyme (Cre) is a member of the extensive family of recombinases and recognizes a 34 bp sequence motif from PI bacteriophage referred to as LoxP. The Cre enzyme works to cleanly excise an intervening DNA fragment that is flan... Read more.
|Cre/Lox: The Genomic Utility Knife
Cre (Cyclization recombination enzyme) is a member of the large family of recombinases. Cre recognizes Lox site loxP, a 34 bp sequence motif from the PI bateriophage. If a DNA segment is flanked by two loxP sites in the same orientation, Cre neatly ex... Read more.
|LOX propeptide: A novel peptide cancer therapeutic
Lysyl oxidase, also known as LOX, is a copper-dependent enzyme that cross-links collagen and elastin through the oxidative deamination of peptidyl lysine (collagen and elastin) and hydroxylysine (collagen only) residues, thereby playing a critical rol... Read more.