Lnx1 Antibody (OTI1H9) [mFluor Violet 500 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI1H9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

Lnx1 Antibody (OTI1H9) [mFluor Violet 500 SE] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 260-528 of human LNX1 (NP_116011) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LNX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-72517. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Lnx1 Antibody (OTI1H9) [mFluor Violet 500 SE]

• EC 6.3.2.-
• ligand of numb-protein X 1ligand of numb-protein X
• LNXmulti-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX
• MPDZ
• Numb-binding protein 1
• PDZ domain-containing ring finger protein 2
• PDZRN2E3 ubiquitin-protein ligase LNX

Background

Lnx1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LNX1