Lnx1 Products

Description

This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq]. Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (b, also known as LNXp70) contains a distinct N-terminus and is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	84708
Alternate Names	EC 6.3.2.- ligand of numb-protein X 1ligand of numb-protein X LNXmulti-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX MPDZ Numb-binding protein 1 PDZ domain-containing ring finger protein 2 PDZRN2E3 ubiquitin-protein ligase LNX

Research Areas for Lnx1

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Zinc Finger