Lnx1 Antibody (OTI1H9) [Alexa Fluor® 350]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI1H9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

Lnx1 Antibody (OTI1H9) [Alexa Fluor® 350] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 260-528 of human Lnx1 (NP_116011) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LNX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Lnx1 Antibody (OTI1H9) [Alexa Fluor® 350]

• EC 6.3.2.-
• ligand of numb-protein X 1ligand of numb-protein X
• LNXmulti-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX
• MPDZ
• Numb-binding protein 1
• PDZ domain-containing ring finger protein 2
• PDZRN2E3 ubiquitin-protein ligase LNX

Background

Lnx1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LNX1