LMTK2 Antibody [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 594

LMTK2 Antibody [Alexa Fluor™ Plus 594] Summary

• Immunogen: The immunogen this antibody was made to, maps to a region between residue 675 to 725 of human Lemur Tyrosine Kinase 2 using the numbering given in entry NP_055731.2 (GeneID 22853).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LMTK2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for LMTK2 Antibody [Alexa Fluor™ Plus 594]

• AATK2
• AATYK2FLJ46659
• Apoptosis-associated tyrosine kinase 2
• Brain-enriched kinase
• BREK
• BREKCDK5/p35-regulated kinase
• CPRK
• EC 2.7.11
• KIAA1079hBREK
• kinase phosphatase inhibitor 2
• Kinase/phosphatase/inhibitor 2
• KPI-2
• KPI2EC 2.7.11.1
• lemur tyrosine kinase 2Serine/threonine-protein kinase KPI-2
• LMR2
• LMR2cyclin-dependent kinase 5/p35-regulated kinase
• LMTK2
• serine/threonine-protein kinase LMTK2

Background

The protein encoded by the LMTK2 gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LMTK2