Lipin 2 Antibody [Alexa Fluor® 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

Lipin 2 Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human Lipin 2
  Ser439-Lys563
  Accession # Q92539
• Specificity: Detects Lipin 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Lipin 1 and rhLipin 3 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Lipin 2 Antibody [Alexa Fluor® 488]

• EC 3.1.3.4
• KIAA0249lipin-2
• Lipin 2
• Lipin-2
• LPIN2
• phosphatidate phosphatase LPIN2

Background

Human Lipin 2 is a 100 kDa (896 aa) nuclear protein that belongs to the large, evolutionarily conserved Lipin family. All Lipin family members have a conserved N‑lipin domain at the N‑termini, a nuclear localization signal, and a conserved C-lipin domain near the C-termini. The functions of the N- and C-lipin domain are not known. Lipin 2 is widely expressed. Mutations in human Lipin 2 have been associated with autosomal dominant high grade myopia and Majeed syndrome. Over the region used as immunogen, human and mouse Lipin 2 are 100% identical. Lipin 2 also shares approximately 48% - 50% amino acid sequence identity with Lipin 1 and Lipin 3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.