Lgr6 Blocking Peptide


There are currently no images for Lgr6 Protein (NBP1-49695PEP).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity HuSpecies Glossary
Applications AC
2.5 mg/ml

Order Details

Lgr6 Blocking Peptide Summary

A peptide corresponding to amino acids 840 - 900 of human LGR6.

GenBank Accession #: CAI15929.1

Source: Synthetic

The peptide sequence corresponding to amino acids 860-915 of the human Lgr6 protein
Protein/Peptide Type
Blocking Peptide
>85%, by HPLC


Application Notes
This peptide is useful as a blocking peptide for NBP1-49695. For further blocking peptide related protocol, click here.
Theoretical MW
104 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
Sodium Bicarbonate buffer, pH 8.00 containing up to 10% DMSO
2.5 mg/ml
>85%, by HPLC

Alternate Names for Lgr6 Blocking Peptide

  • FLJ14471
  • gonadotropin receptor
  • GPCR
  • leucine-rich repeat containing G protein-coupled receptor 6
  • leucine-rich repeat-containing G protein-coupled receptor 6
  • leucine-rich repeat-containing G-protein coupled receptor 6
  • Lgr6
  • VTS20631


Relaxin family peptides which closely resembles insulin, act on a group of G-protein-coupled receptors now known as relaxin family peptide (RXFP) receptors. The leucine-rich repeat containing RXFP1 and RXFP2 and the small peptide-like RXFP3 and RXFP4 are the physiological targets for relaxin, insulin-like (INSL) peptide 3, relaxin-3 and INSL5, respectively. Leucine rich repeat containing GPCR (Lgr6) is a member of the same large family of GPCR (Lgr1-Lgr16) that binds to variety of glycoprotein hormones like TSH, FSH, LH (1). This family of receptor is unique in having a large ectodomain important for ligand binding. The large extracelluar domain binds the ligands with high affinity; there also exist a low affinity binding site in the exoloop of the trnasmembrane region. LGR6 has a subgroup-specific hinge region after leucine-rich repeats whereas LGR7, like snail LGR, contains a low density lipoprotein (LDL) receptor cysteine-rich motif at the N terminus. The expression of LGR5 is induced in the limb, tail, and intestine by T3 during metamorphosis of frog form larval stage. More importantly, LGR5 mRNA is localized to the developing adult epithelial stem cells of the intestine (2). Lgr6 are also involved in transcription silencing of CpG islands by hypermethylation in colorectal cancer which are referred as methylator phenotypes. The CAN genes include SYNE1, STRAD8, CD109, RNF, RET, APC2 MMP2, PTPRD and Lgr6 (3). Lgr5 is a marker for cycling stem cells in intestine (4) whereas Lgr6 is expressed in earliest embryonic hair placodes (5).Lgr6 positive cells are also involved in wound healing. In adult hair follicles the Lgr6 resides in a region just above the follicle bulge, this region was previously uncharacterized and does not express any known bulge stem cell markers. The Lgr6 is a marker for a distinct population of stem cells that give rise to all lineages of the skin. Unlike Lgr5, the Lgr6 is not regulated by Wnt signaling. The Lgr6-selective antibodies were generated against antigenic peptide taken from human Lgr6 protein corresponding near to carboxy terminal Lgr6 protein. Lgr6-antibodies are affinity purified over immobilized antigen based chromatography, and the purified immunoglobulins are stabilized in antibody stabilization buffer.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC, IP, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ELISA(Sta)
Species: Hu, Mu, Rt
Applications: WB, IHC
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Pm
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Rt
Applications: WB, IHC, IHC-P
Species: Hu
Applications: AC

Publications for Lgr6 Protein (NBP1-49695PEP) (0)

There are no publications for Lgr6 Protein (NBP1-49695PEP).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Lgr6 Protein (NBP1-49695PEP) (0)

There are no reviews for Lgr6 Protein (NBP1-49695PEP). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for Lgr6 Protein (NBP1-49695PEP) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional Lgr6 Products

Bioinformatics Tool for Lgr6 Protein (NBP1-49695PEP)

Discover related pathways, diseases and genes to Lgr6 Protein (NBP1-49695PEP). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Lgr6 Protein (NBP1-49695PEP)

Discover more about diseases related to Lgr6 Protein (NBP1-49695PEP).

Pathways for Lgr6 Protein (NBP1-49695PEP)

View related products by pathway.

PTMs for Lgr6 Protein (NBP1-49695PEP)

Learn more about PTMs related to Lgr6 Protein (NBP1-49695PEP).

Research Areas for Lgr6 Protein (NBP1-49695PEP)

Find related products by research area.

Blogs on Lgr6

There are no specific blogs for Lgr6, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)

As an example, if the molecular weight of a compound is 197.13 g/mol and the desired concentration is 10 mM for 10 ml of water based stock solution, the required mass would be = 19.713 (value determined by this calculator).


Review this Product

Be the first to review our Lgr6 Blocking Peptide and receive a gift card or discount.


Gene Symbol LGR6