Leupaxin Antibody

Western Blot: Leupaxin Antibody [NBP3-23403] - Western blot analysis of leupaxin in human PC-3, rat A7r5, and human A431 cells. The blot was probed with anti-Leupaxin (N-terminal region) at 1:1000 (Lanes 1-3). Anti-Actin molecular weight standard is shown in lane 4.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Leupaxin Antibody Summary

• Description: Stable for at least 1 year at -20°C.
• Immunogen: Leupaxin (N-terminal) synthetic peptide (coupled to KLH) corresponding to amino acid residues in the N-terminal region of human leupaxin. This peptide sequence is highly conserved in rat and mouse leupaxin, and has low homology to other paxillin family proteins. [UniProt# O60711]
• Specificity: The antibody detects a 45 kDa proteins corresponding to the apparent molecular mass of leupaxin on SDS-PAGE immunoblots of human A431 epithelial cells, human PC3 prostate cells, and rat A7r5 smooth muscle cells.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LPXN
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Theoretical MW: 45 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C.
• Buffer: PBS, 1 mg/ml BSA and 50% glycerol
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Leupaxin Antibody

• LDLP
• LDPL
• leupaxin

Background

The product encoded by this gene is preferentially expressed in hematopoietic cells and is most homologous to the focal adhesion protein, paxillin. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by tyrosine kinase activity. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LPXN