LDOC1 Antibody - BSA Free

Western Blot: LDOC1 Antibody [NBP1-80323] - Host: Rabbit. Target: LDOC1. Positive control (+): MCF7 (N10). Negative control (-): HeLa (HL). Antibody concentration: 3ug/ml

Immunohistochemistry: LDOC1 Antibody [NBP1-80323] - Human Thyroid lysate tissue at an antibody concentration of 5.0 ug/ml using anti-LDOC1 antibody

Western Blot: LDOC1 Antibody [NBP1-80323] - HepG2 cell lysate, Antibody Titration: 0.2-1 ug/ml

Immunohistochemistry: LDOC1 Antibody [NBP1-80323] - Human brain, cortex tissue at an antibody concentration of 5.0 ug/ml using anti-LDOC1 antibody

Immunohistochemistry: LDOC1 Antibody [NBP1-80323] - Human breast tissue at an antibody concentration of 5.0 ug/ml using anti-LDOC1 antibody

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

LDOC1 Antibody - BSA Free Summary

• Description: The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
• Immunogen: Synthetic peptide directed towards the N terminal of human LDOC1. Peptide sequence MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCP. The peptide sequence for this immunogen was taken from within the described region.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LDOC1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 2% Sucrose
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Affinity purified

Alternate Names for LDOC1 Antibody - BSA Free

• BCUR1
• breast cancer, up-regulated 1
• Leucine zipper protein down-regulated in cancer cells
• leucine zipper, down-regulated in cancer 1
• Mar7
• Mart7
• protein LDOC1

Background

LDOC1, also known as Protein LDOC1, is a 146 amino acid protein that is 17 kDa, nucleus located, down-regulated in some cancer cell lines, thought to act as a regulator of the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB), and may participate in the development and/or progression of some cancers. This protein is currently being studied for research on the following diseases and disorders: breast cancer, cryptorchidism, chronic lymphocytic leukemia, lymphocytic leukemia, pancreatic cancer, thyroiditis, pancreatitis, and leukemia. Interactions with LDOC1 protein have been shown to involve over 40 proteins including FXR2, ABLIM1, NRIP1, FOSL1, and CCDC858 proteins in negative regulation of cell proliferation pathwyas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LDOC1 Antibody (NBP1-80323)(2)

Publications using NBP1-80323

• Salemi M, Barone C, Romano C, Caniglia S. LDOC1 expression in fibroblasts of patients with Down syndrome Open Life Sci 2015-01-01 (WB, Human)
• Salemi M, Barone N, La Vignera S et al. Leucine zipper, down regulated in cancer-1 gene expression in prostate cancer. Oncol Lett. 2016-10-01 [PMID: 27698860] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: LDOC1
• Uniprot:
  • NP_036449(Human)