SPANXA1 Antibody - BSA Free

Western Blot: SPANXA1 Antibody - BSA Free [NBP3-45851] - DU 145 cells were subjected to SDS PAGE followed by western blot with (SPANXA1 antibody) at dilution of 1:500

Immunohistochemistry: SPANXA1 Antibody - BSA Free [NBP3-45851] - Immunohistochemistry of paraffin-embedded human testis tissue slide using (SPANXA1 Antibody) at dilution of 1:50

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SPANXA1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SPANXA1 Antibody - BSA Free (NBP3-45851) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: SPANX family, member A2. (Uniprot# Q9NS26)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SPANXA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:10-1:100
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:1000
• Theoretical MW: 27 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for SPANXA1 Antibody - BSA Free

• B1
• C
• cancer/testis antigen family 11, member 1
• CT11.1
• CT11.2
• CT11.3
• CT11.4
• CTp11
• dJ171K16.1
• member A1
• NAP-X
• nuclear-associated protein SPAN-Xa
• SPANX family member A
• SPANX
• SPAN-X
• SPANXA
• SPAN-Xa
• SPANX-A
• SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1
• SPANXA2
• SPANX-A2
• SPANXB
• SPAN-Xb
• SPANX-B
• SPANXC
• SPANX-C
• SPANXD
• SPANX-D
• sperm protein associated with the nucleus on the X chromosome A
• sperm protein associated with the nucleus, X chromosome, family member A1
• sperm protein associated with the nucleus, X-linked, family member A1

Background

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPANXA1