Recombinant Human Latexin Protein

Images

 
Western Blot: LXN Protein [NBC1-21278] - Human Recombinant E.coli

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human Latexin Protein Summary

Description
An un-tagged recombinant protein corresponding to the amino acids 1-222 of Human Latexin

Source: E.coli

Amino Acid Sequence: MEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYRLKFAVEE IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
LXN
Purity
>95% pure by SDS-PAGE
Endotoxin Note
< 1.0 EU per 1 microgram of protein (determined by LAL method)

Applications/Dilutions

Theoretical MW
25.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 7.5) containing 50mM NaCl, 10% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human Latexin Protein

  • ECI
  • ECIMUM
  • Endogenous carboxypeptidase inhibitor
  • Latexin
  • LXN
  • TCI
  • TCIProtein MUM
  • Tissue carboxypeptidase inhibitor

Background

Latexin, a carboxypeptidase A inhibitor, is highly expressed in heart, prostate, ovary, kidney, pancrease, and colon, moderaqte or low in other tissues including brain. Latexin has no detectable sequence similarity with plant and parasite inhibitors, but it is related to a human putative tumor suppressor protein, TIG1. It is down-regulated in the presenilin-1-deficient mouse brain, thus putatively playing a role in Alzheimer's disease. Recombinant human Latexin protein was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol LXN
Entrez