LAMP Antibody [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: CoraFluor 1

LAMP Antibody [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human LAMP
  Val29-Asn315
  Accession # AAC50569
• Specificity: Detects human LAMP in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: LSAMP
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for LAMP Antibody [CoraFluor™ 1]

• FLJ34254
• FLJ35396
• IgLON family member 3
• IGLON3FLJ54658
• LAMP
• LAMPFLJ37216
• limbic system-associated membrane protein
• LSAMP

Background

LSAMP, also known as Limbic system-associated membrane protein, is a 338 amino acid protein that is 53 kDa, expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal cord and cerebellum; mediates selective neuronal growth and axon targeting, contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system, vital for normal growth of the hyppocampal mossy fiber projection. Current research is being performed on several diseases and disorders including neuronitis, clear cell renal cell carcinoma, bipolar disorder, osteosarcoma, renal cell carcinoma, cerebritis, schizophrenia, and carcinoma. This protein has been shown to interact with PPNP, YWHAB, PPP2CB, DHX9, and STX16 in cell adhesion and nervous system development pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LSAMP