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LAIR2 Antibody (319701) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
319701
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
IC2665V-100UG
Alexa Fluor 488
IC2665G-100UG
Alexa Fluor 594
IC2665T-100UG
Alexa Fluor 647
IC2665R-100UG
Alexa Fluor 700
IC2665N-100UG
Alexa Fluor 750
IC2665S-100UG
Unconjugated
MAB2665
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2665
Carrier Free
MAB2665
Carrier Free
MAB2665-SP
Carrier Free
IC2665V-100UG
Carrier Free
IC2665T-100UG
Carrier Free
IC2665S-100UG
Carrier Free
IC2665R-100UG
Carrier Free
IC2665N-100UG
Carrier Free
IC2665G-100UG
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LAIR2 Antibody (319701) [Alexa Fluor® 350] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LAIR2 isoform 1
Gln22-Pro152
Accession # Q6ISS4
Specificity
Detects human LAIR2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human LAIR1, recombinant mouse (rm) LAIR1 or rmLAIR2 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
LAIR2
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LAIR2 Antibody (319701) [Alexa Fluor® 350]

  • CD306 antigen
  • CD306
  • CD306leukocyte-associated Ig-like receptor-2
  • LAIR2
  • LAIR-2
  • leukocyte-associated Ig-like receptor 2
  • leukocyte-associated immunoglobulin-like receptor 2
  • MGC71634

Background

LAIR2 (leukocyte-associated Ig-like receptor-2; CD306) is a secreted, 131 amino acid (aa) protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR1, its transmembrane counterpart, it shares 83% aa identity across the signal sequence and extracellular domains (1‑3). Although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR2 may compete with LAIR1 for ligand binding (3, 4). A 114 aa alternate splice form of LAIR2 is truncated at the C terminus, but retains the entire Ig domain (1‑3). The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.

  1. Meyaard, L. (2003) J. Biol. Regul. Homeost. Agents 17:330.
  2. Meyaard, L. et al. (1999) J. Immunol. 162:5800.
  3. Meyaard, L. et al. (1997)  Immunity 7:283.
  4. Xu, X.G. et al. (2005) Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 21:553.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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LAIR2 Antibody
(319701) [Alexa Fluor ...
IC2665U
LAIR2 Antibody (319701) [Alexa Fluor® 350]
Species: Hu
Applications: Flow

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 IC2665U
Alexa Fluor 405 IC2665V
Alexa Fluor 488 IC2665G
Alexa Fluor 594 IC2665T
Alexa Fluor 647 IC2665R
Alexa Fluor 700 IC2665N
Alexa Fluor 750 IC2665S
Learn about Custom Antibody Labeling

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Bioinformatics

Gene Symbol LAIR2
Uniprot