LAIR1 Antibody (113) [HRP]

• Reactivity: Mu
• Applications: WB, Flow, IP
• Clone: 113
• Clonality: Monoclonal
• Host: Armenian Hamster
• Conjugate: HRP

LAIR1 Antibody (113) [HRP] Summary

• Immunogen: The immunogen for this antibody was CD305.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Armenian Hamster
• Gene: LAIR1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
• Application Notes: This 113 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Alternate Names for LAIR1 Antibody (113) [HRP]

• CD305 antigen
• CD305
• CD305leukocyte-associated Ig-like receptor 1
• HLAIR1
• LAIR1
• LAIR-1
• leukocyte-associated immunoglobulin-like receptor 1

Background

LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LAIR1 Antibody (NBP1-43324H)(1)

Publication using NBP1-43324H

• Myers LK, Ouyang YX, Patel JR et al. Role of Citrullinated Collagen in Autoimmune Arthritis International journal of molecular sciences 2022-08-30 [PMID: 36077232] (Western Blot)

Bioinformatics

• Gene Symbol: LAIR1