WB, ICC/IF, IHC, IHC-PHost:
WB, Flow, CyTOF-readyHost:
Applications: WB, Flow, IP
Host: Mouse Monoclonal
LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.
Bioinformatics Tool for LAIR1
Discover related pathways, diseases and genes to LAIR1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.