LAIR1 Products

Description

LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.

Bioinformatics

Entrez	3903 Human
Uniprot	AAH27899 Human NP_002278 Human NP_002278.1 Human Q6GTX8 Human NM_002287 Human NP_068352 Human
Product By Gene ID	3903
Alternate Names	CD305 antigen hLAIR1 LAIR-1 CD305leukocyte-associated Ig-like receptor 1 leukocyte-associated immunoglobulin-like receptor 1

Diseases related to LAIR1

Discover more about diseases related to LAIR1.

Tissue Adhesions
Leukemia
Liver Diseases
Sclerosis
Hepatitis, Chronic
Hypoxia
Diffuse Scleroderma
Lymphocytosis
Malignant Neoplasms
Neoplasms
Lymphopenia
Lupus Erythematosus, Systemic
Allergy
Liver Dysfunction
Cytogenetic Abnormality
Rheumatoid Arthritis
Chronic Lymphocytic Leukemia
Hepatitis
Liver Failure

Pathways for LAIR1

View related products by pathway and learn more about each of the pathways below.

Leukocyte Differentiation
Cell Adhesion
Chemotaxis
Programmed Cell Death
Cell Death
Pathogenesis
Secretion

Bioinformatics Tool for LAIR1

Discover related pathways, diseases and genes to LAIR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.