Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: WB, Flow, IP
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Mu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
3903 |
Alternate Names |
- CD305 antigen
- hLAIR1
- LAIR-1
- CD305leukocyte-associated Ig-like receptor 1
- leukocyte-associated immunoglobulin-like receptor 1
|
Bioinformatics Tool for LAIR1
Discover related pathways, diseases and genes to LAIR1. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.