Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow, IP
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Pm-Cm
Applications: Bioactivity
Description
LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
3903 |
| Alternate Names |
- CD305 antigen
- CD305leukocyte-associated Ig-like receptor 1
- hLAIR1
- LAIR-1
- leukocyte-associated immunoglobulin-like receptor 1
|
![Flow Cytometry LAIR1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af2664_human-lair1-affinity-purified-polyclonal-ab-flow-cytometry-1912202412592..jpg)
![N/A LAIR1 [Biotin]](http://images.novusbio.com/fullsize2/dy2664-05_human-lair1-duoset-elisa-5-plate-181202112238.jpg)
![Binding Activity LAIR1 [Biotin]](http://images.novusbio.com/fullsize2/LAIR1_AVI2664_2862.jpg)
![SDS-PAGE LAIR1 [Biotin]](http://images.novusbio.com/fullsize2/LAIR1_AVI2664_2611.jpg)
![Binding Activity LAIR1 [Unconjugated]](http://images.novusbio.com/fullsize2/LAIR1_9964LR_2067.jpg)
![SDS-PAGE LAIR1 [Unconjugated]](http://images.novusbio.com/fullsize2/LAIR1_9964LR_2029.jpg)
![Binding Activity LAIR1 [Unconjugated]](http://images.novusbio.com/fullsize2/LAIR1_10226LR_2773.jpg)
![SDS-PAGE LAIR1 [Unconjugated]](http://images.novusbio.com/fullsize2/LAIR1_10226LR_2640.jpg)