LAIR1 Products

Antibodies
LAIR1 Antibody
LAIR1 Antibody
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LAIR1 Antibody [Unconjugated] ...
LAIR1 Antibody [Unconjugated]
AF2664
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
LAIR1 Antibody (2459C) [Uncon ...
LAIR1 Antibody (2459C) [Unconjugated]
MAB10092
Species: Mu
Applications: WB
Host: Rabbit Monoclonal
Formulation Catalog # Availability Price  
Lysates
LAIR1 Overexpression Lysate
LAIR1 Overexpression Lysate
NBL1-12426
Species: Hu
Applications: WB
Proteins
Recombinant Human LAIR1 Fc Ch ...
Recombinant Human LAIR1 Fc Chimera...
9964-LR
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Cynomolgus LAIR1 ...
Recombinant Cynomolgus LAIR1 Fc Ch...
10226-LR
Species: Pm-Cm
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human LAIR1 His-t ...
Recombinant Human LAIR1 His-tag Av...
AVI2664
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  

Description

LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 3903
Alternate Names
  • CD305 antigen
  • hLAIR1
  • LAIR-1
  • CD305leukocyte-associated Ig-like receptor 1
  • leukocyte-associated immunoglobulin-like receptor 1

Pathways for LAIR1

View related products by pathway and learn more about each of the pathways below.

Leukocyte Differentiation
Cell Adhesion
Chemotaxis
Programmed Cell Death
Cell Death
Pathogenesis
Secretion

Bioinformatics Tool for LAIR1

Discover related pathways, diseases and genes to LAIR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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