Kv7.2 Antibody - Azide and BSA Free

Western Blot: Kv7.2 Antibody [NBP3-03616] - Western blot analysis of extracts of various cell lines, using Kv7.2 antibody (NBP3-03616) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Kv7.2 Antibody - Azide and BSA Free Summary

• Description: Novus Biologicals Rabbit Kv7.2 Antibody - Azide and BSA Free (NBP3-03616) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 466-665 of human Kv7.2 (NP_742105.1). SPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNQ2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.01% Thimerosal
• Purity: Affinity purified

Alternate Names for Kv7.2 Antibody - Azide and BSA Free

• BFNC
• BFNS1
• EBN
• EBN1
• EIEE7
• ENB1
• HNSPC
• KCNA11
• KCNQ2
• KQT-like 2
• Kv7.2
• KVEBN1
• neuroblastoma-specific potassium channel protein
• Neuroblastoma-specific potassium channel subunit alpha KvLQT2
• potassium voltage-gated channel subfamily KQT member 2
• potassium voltage-gated channel, KQT-like subfamily, member 2
• Voltage-gated potassium channel subunit Kv7.2

Background

KCNQs are members of the voltage dependent non inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1 to 5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M current. Inhibition of M current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Bioinformatics

• Gene Symbol: KCNQ2