Kv7.2 Products

Description

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.

Bioinformatics

Entrez	3785 Human
Uniprot	NP_742107.1 Human
Product By Gene ID	3785
Alternate Names	BFNC BFNS1 EBN EBN1 EIEE7 ENB1 HNSPC KCNA11 KCNQ2 KQT-like 2 Kv7.2 KVEBN1 neuroblastoma-specific potassium channel protein Neuroblastoma-specific potassium channel subunit alpha KvLQT2 potassium voltage-gated channel subfamily KQT member 2 potassium voltage-gated channel, KQT-like subfamily, member 2 Voltage-gated potassium channel subunit Kv7.2

Research Areas for Kv7.2

Find related products by research area and learn more about each of the different research areas below.

Neurodegeneration
Neuroscience