Kv7.2 Products

Description

KCNQs are members of the voltage dependent non inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1 to 5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M current. Inhibition of M current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Bioinformatics

Entrez	3785 Human
Uniprot	AAH00699 Human NP_742105 Human
Product By Gene ID	3785
Alternate Names	BFNC BFNS1 EBN EBN1 EIEE7 ENB1 HNSPC KCNA11 KQT-like 2 KV7.2 Kv7.2 KVEBN1 neuroblastoma-specific potassium channel protein Neuroblastoma-specific potassium channel subunit alpha KvLQT2 potassium voltage-gated channel subfamily KQT member 2 potassium voltage-gated channel, KQT-like subfamily, member 2 Voltage-gated potassium channel subunit Kv7.2

Diseases related to Kv7.2

Discover more about diseases related to Kv7.2.

Epilepsy
Convulsion Neonatal
Familial Benign Neonatal Epilepsy
Convulsions
Benign Neonatal Epilepsy
Epilepsy, Generalized
Pain
Nervousness
Febrile Convulsions
Myokymia
Channelopathies
Epilepsies, Myoclonic
Neuralgia
Autosomal Dominant Form Of Benign Neonatal Seizures
Long Qt Syndrome
Epilepsy, Frontal Lobe
Epilepsies, Partial
Tonic-clonic Epilepsy

Pathways for Kv7.2

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Localization
Membrane Depolarization
Transport
Cognition
Hypersensitivity
Exocytosis
Brain Development
Sensitization
Glycosylation
Lipid Phosphorylation
Protein Phosphorylation
Muscle Contraction
Neurogenesis
Transepithelial Transport
Protein Glycosylation
Swimming
Reverse Transcription
Translation
Gliogenesis

PTMs for Kv7.2

Learn more about PTMs related to Kv7.2.

Phosphorylation
Reduction
Glycosylation
Cleavage
Ubiquitination
Biotinylation
Dephosphorylation
Ribosylation

Bioinformatics Tool for Kv7.2

Discover related pathways, diseases and genes to Kv7.2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.