Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Ha
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
KCNQs are members of the voltage dependent non inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1 to 5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M current. Inhibition of M current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
3785 |
Alternate Names |
- BFNC
- BFNS1
- EBN
- EBN1
- EIEE7
- ENB1
- HNSPC
- KCNA11
- KQT-like 2
- KV7.2
- Kv7.2
- KVEBN1
- neuroblastoma-specific potassium channel protein
- Neuroblastoma-specific potassium channel subunit alpha KvLQT2
- potassium voltage-gated channel subfamily KQT member 2
- potassium voltage-gated channel, KQT-like subfamily, member 2
- Voltage-gated potassium channel subunit Kv7.2
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